P0300 on a GMC: Causes, Fixes & Repair Cost

🟠 Moderate severity · drivable

If the check engine light is flashing, stop driving — a severe misfire can damage the catalytic converter. A steady light is usually safe for a short drive to a shop.

What P0300 means on a GMC

On a GMC, P0300 means the engine computer sees misfires jumping between cylinders instead of on one fixed cylinder. A misfire means a cylinder is not burning its fuel properly, which wastes gas and can damage the catalytic converter if left alone.

Is P0300 common on GMCs?

P0300 is common on GMC trucks and SUVs with the 4.8L, 5.3L, and 6.0L V8s. Worn spark plugs and ignition coils are the usual causes at higher mileage. Intake manifold gasket leaks and fuel injector issues also trigger random misfires on these engines.

Commonly reported on: Sierra, Yukon, Canyon, Acadia.

Symptoms

Check engine light on (flashing if severe)
Rough idle or shaking engine
Loss of power or hesitation
Poor fuel economy

Common causes

most common: Worn or fouled spark plugs
common: Failing ignition coils
common: Leaking intake manifold gaskets
less common: Clogged fuel injectors or low fuel pressure
less common: Low compression from engine wear

How to fix it

Fix	DIY?	Typical cost
Replace worn spark plugs	Yes	$60–250
Replace failing ignition coils	Yes	$100–350
Replace leaking intake manifold gaskets	Mechanic	$300–700
Run a compression test to rule out internal engine wear	Mechanic	$100–200